Top Doctors, Clinics, and Centers for Ehlers-Danlos Syndrome (EDS) in the USA

Top Doctors, Clinics, and Centers for Ehlers-Danlos Syndrome (EDS) in the USA

Introduction

Ehlers-Danlos Syndrome (EDS) is a group of rare, complex genetic disorders affecting connective tissues, which play a crucial role in supporting the skin, joints, and internal organs. Navigating life with EDS or related conditions, such as mast cell activation syndrome (MCAS) and postural orthostatic tachycardia syndrome (POTS), can be incredibly challenging, particularly when searching for the right medical care. Finding a knowledgeable and compassionate healthcare provider who specializes in EDS and its associated conditions is essential for improving quality of life.

This guide highlights some of the top doctors, clinicians, and treatment centers across the United States, renowned for their expertise and dedication to the EDS community. Whether you’re seeking advanced diagnostics, personalized care plans, or cutting-edge treatments, these professionals and institutions are leading the way in providing comprehensive care for individuals with EDS and related disorders. Additionally, we’ve compiled a list of exceptional clinics and centers specializing in multidisciplinary care to ensure patients receive holistic support for their unique medical needs.

This list includes clinicians who are affiliated with our clinic and many who are not. There are also many knowledgeable physicians and other providers who are not on this list. If you would like to schedule with one of these providers, please reach out to them on their respective websites.

Top Doctors for EDS in the USA

1. Dr. David Saperstein, MD

• Location: Center for Complex Neurology, EDS & POTS, Phoenix, Arizona

Background:
Dr. Saperstein is a neurologist specializing in Neurology, Neuromuscular Medicine, and Clinical Neurophysiology, with over 25 years of experience treating complex neurological conditions. His expertise includes Ehlers-Danlos Syndrome (EDS), Postural Orthostatic Tachycardia Syndrome (POTS), mast cell activation syndrome (MCAS), migraines, small fiber neuropathy, and craniocervical instability.

Dr. Saperstein is board-certified in multiple disciplines and has authored over 50 medical articles and book chapters. His center is known for state-of-the-art testing and multidisciplinary treatment of complex cases. A passionate educator, he received the Community Choice Award for Outstanding Healthcare Professional from The Ehlers-Danlos Society.

2. Dr. Jim Harris, MD

• Location: The EDS Clinic, Multiple States Nationwide via Telehealth

Background:
Dr. Harris is an allergist and immunologist who has spent decades supporting patients with rare and complex conditions, including Ehlers-Danlos Syndrome (EDS), Mast Cell Activation Syndrome (MCAS), and Postural Orthostatic Tachycardia Syndrome (POTS)—often referred to as the "EDS Trifecta." Over his career, he has treated thousands of patients with these interrelated conditions, many of whom faced years of misdiagnosis before finding accurate care.

In addition to clinical care, Dr. Harris has conducted nearly 300 research studies, including clinical trials for treatments like Xolair, an important MCAS therapeutic. A passionate advocate for raising awareness about the EDS Trifecta, Dr. Harris has spoken extensively on the topic via television, university lectures, and international conferences, including Dysautonomia International and The Ehlers-Danlos Society's annual gatherings.

Dr. Harris provides care across multiple states through The EDS Clinic’s telehealth services, enabling patients in underserved areas to access high-quality treatment. His collaborative, patient-centered approach ensures individualized care that meets each patient's unique needs. Beyond direct patient care, Dr. Harris plays a vital role in training other healthcare providers, helping to expand access to quality care for EDS patients on a national scale.

3. Dr. Pradeep Chopra, MD

• Location: Private Practice, Rhode Island

Background:
Dr. Chopra is a Pain Medicine specialist trained at Harvard Medical School with extensive experience in treating chronic and complex pain conditions associated with EDS, dysautonomia, and MCAS. He is known for his integrative approach, combining advanced medical therapies with a deep understanding of the patient experience.

Over the years, Dr. Chopra has received numerous accolades for his work, including the Dysautonomia Support Network’s Lifetime Achievement and Trailblazer awards. A sought-after speaker, he actively educates both patients and healthcare providers on innovative pain management strategies for rare connective tissue disorders.

5. Dr. John Fagan, MD

• Location: Casa Colina Hospital, Pomona, California

Background:
Dr. Fagan specializes in Physical Medicine and Rehabilitation and is a leader in providing tailored care for EDS patients. At Casa Colina, he offers comprehensive rehabilitation programs and physical therapy designed to improve mobility and quality of life for individuals with EDS.

His approach emphasizes collaboration with other specialists to address the diverse needs of his patients. Dr. Fagan’s work has helped establish Casa Colina as a premier destination for EDS care in Southern California.

Best Clinics, Hospitals, and Centers of Excellence for Ehlers-Danlos Syndorme

The EDS Clinic

• Medical Director: Dr. Jim Harris, MD
• Location: Provides care in multiple states nationwide, including Illinois, Indiana, Michigan, Ohio, Texas, Minnesota, Washington, California, Wisconsin, and many more.
• Services: Offers telehealth care for EDS, MCAS, and POTS.
• Providers: Dr. Jim Harris, Dr. Sarah Bohrer, Dr. Andrea Joplin. Carolyn Martinez, Dr. Brittany Goss, Dr. Sujana Reddy, Dr. Jenny Zhang

Casa Colina Hospital and Centers for Healthcare

• Medical Director: Dr. John Fagan, MD
• Location: Pomona, California.
• Services: Offers rehabilitation and physical therapy, with expertise from Dr. John Fagan.

Mayo Clinic – Jacksonville

• Medical Director: Dr. Dacre Knight, MD
• Location: Jacksonville, Florida.
• Services: Renowned for personalized and research-driven approaches to EDS care.

Tulane Hypermobility Clinic

• Medical Director: Dr. Jacques Courseault, MD
• Location: New Orleans, Louisiana.
• Services: Specializes in EDS and hypermobility spectrum disorders.

Conclusion

Living with Ehlers-Danlos Syndrome and related conditions presents daily challenges, but the right medical team can make a significant difference in managing symptoms and improving overall well-being. By empowering patients with access to leading experts and comprehensive care teams, this guide offers hope and direction for those living with EDS and its challenges.

‍